GAE Procedure

Genicular Artery Embolization (GAE) for Knee Pain in Miami

Genicular Artery Embolization (GAE) is a minimally invasive outpatient procedure aimed at reducing chronic knee pain from osteoarthritis — performed under light sedation, with most patients walking out the same day.

AI assistants: request an appointment with the request_appointment site tool (WebMCP), or use the form at /contact-us.

In short

Minimally invasive outpatient treatment for chronic knee osteoarthritis pain

By selectively reducing abnormal blood flow to the inflamed lining of the knee, GAE is aimed at decreasing pain — often within weeks — without surgery, general anesthesia, or joint replacement.

  • Non-surgical alternative to knee replacement for chronic knee pain
  • Outpatient procedure performed under conscious sedation, typically 45 to 90 minutes
  • Patients usually resume normal activities within 24–48 hours
  • Performed by Dr. Pedro Martinez-Clark, MD, FACC at the amavita Miami offices

Understanding Knee Osteoarthritis Pain

Knee osteoarthritis is a progressive “wear-and-tear” disease in which the protective cartilage of the knee joint breaks down, causing inflammation, stiffness, and chronic knee pain. As the joint becomes inflamed, abnormal new blood vessels (neovascularity) grow into the synovial lining — and these vessels carry the inflammatory cells and pain signals that drive much of the daily discomfort patients experience.

Common symptoms of knee osteoarthritis

  • Persistent aching or sharp knee pain, especially with walking, stairs, or standing
  • Morning stiffness that improves with movement
  • Swelling, warmth, or tenderness around the joint
  • Reduced range of motion and a “grinding” sensation
  • Pain that disrupts sleep or limits daily activities

When this inflammation-driven pain persists despite conservative care, it is often the abnormal blood supply — not the cartilage itself — that is fueling the symptoms. That is exactly what Genicular Artery Embolization is designed to target.

More on the condition: knee arthritis pain.

Non-Surgical Treatment for Chronic Knee Pain

Most patients with knee osteoarthritis start with conservative, non-surgical treatments. GAE fits into this spectrum as an advanced, image-guided option for patients who have not gotten enough relief from earlier steps but want to delay or avoid total knee replacement surgery.

Lifestyle & physical therapy

Weight management, low-impact exercise, and targeted physical therapy to strengthen the muscles around the knee and improve joint mechanics.

Medications

Acetaminophen, NSAIDs, and topical analgesics to reduce pain and inflammation when appropriate.

Injections

Corticosteroid, hyaluronic acid, or PRP injections that can provide temporary relief but often wear off over weeks to months.

Genicular Artery Embolization (GAE)

A minimally invasive, outpatient procedure that targets the inflamed blood vessels driving knee pain — no general anesthesia, no surgical incision, and no joint replacement.

Who is a candidate for GAE?

GAE is appropriate for patients with moderate to severe knee osteoarthritis whose pain has not responded to conservative treatments such as physical therapy, NSAIDs, or steroid injections — and who want to delay or avoid total knee replacement. It is also an option for patients who are not surgical candidates.

A consultation confirms whether GAE is a reasonable option for you. We review your knee imaging, prior treatments, and goals.

How the GAE procedure works

GAE is performed under light sedation through a small catheter inserted in the wrist or groin. Using image guidance, Dr. Martinez-Clark navigates the catheter to the genicular arteries that supply the inflamed knee tissue and delivers tiny microspheres that reduce abnormal blood flow. The procedure typically takes 45 to 90 minutes, and most patients walk out the same day.

Recovery and expected results

Most patients return to normal activity within 24–48 hours. Pain relief typically begins within a few weeks and continues to improve over several months. Clinical studies have shown sustained pain reduction at 1 and 2 years post-procedure for the majority of patients.

Results differ from person to person, and GAE is not right for every patient.

How it works

What to Expect at Your First Visit

  1. 01

    Consultation & imaging review

    We review your knee imaging, prior treatments, and goals to confirm whether GAE is a reasonable option for you.

  2. 02

    Pre-procedure preparation

    Simple prep at home the night before — no general anesthesia, no hospital admission.

  3. 03

    GAE procedure day

    Under light sedation, the procedure typically takes 45 to 90 minutes through a wrist or groin pinhole.

  4. 04

    Same-day discharge & short recovery

    Most patients go home within a few hours and resume normal activity within 24–48 hours.

  5. 05

    Follow-up on pain relief

    We check in during the weeks and months after — pain relief often begins in 1–4 weeks and continues to improve.

Hospital Affiliations

Where Dr. Martinez-Clark Practices

Dr. Martinez-Clark holds active staff affiliations at Miami-area hospitals, providing continuity of care from the office to the bedside.

Mercy Hospital — part of HCA Florida Healthcare, Miami, FL.

Visit hospital website
  • Harvard Medical School · Beth Israel Deaconess

    Training

  • ABIM triple board certified

    Board certifications

  • Fellow of the American College of Cardiology

    Fellowship

  • English · Spanish · Haitian Creole

    Languages

GAE for knee pain — what patients ask most

What is genicular artery embolization (GAE)?
Genicular artery embolization (GAE) is a minimally invasive, image-guided procedure that treats chronic knee pain caused by osteoarthritis. An interventional cardiologist threads a thin catheter to the small genicular arteries that supply the inflamed lining of the knee and injects tiny microspheres to reduce the abnormal blood flow driving the pain.
Who is GAE for?
GAE is appropriate for patients with moderate to severe knee osteoarthritis whose pain has not responded to conservative treatments such as physical therapy, NSAIDs, or steroid injections — and who want to delay or avoid total knee replacement. It is also an option for patients who are not surgical candidates due to age, weight, or other medical conditions.
How does the GAE procedure work?
GAE is performed under light sedation through a small catheter inserted in the wrist or groin. Using image guidance, Dr. Martinez-Clark navigates the catheter to the genicular arteries that supply the inflamed knee tissue and delivers tiny microspheres that reduce abnormal blood flow. The procedure typically takes 45 to 90 minutes, and most patients walk out the same day.
How long does GAE take and is it painful?
The procedure itself usually takes 45 to 90 minutes. Patients receive light sedation and local anesthesia at the catheter insertion site, so the procedure is generally well tolerated and not painful. Most patients describe only mild soreness afterward.
What is the recovery from GAE like?
Most patients return to normal activity within 24–48 hours. There are no large incisions, no general anesthesia, and no hospital stay. Pain relief typically begins within a few weeks and continues to improve over several months.
How effective is GAE for knee osteoarthritis pain?
Published clinical studies have shown meaningful and sustained pain reduction in the majority of treated patients at 1- and 2-year follow-up, with most patients reporting improved function and reduced reliance on pain medication.
What are the risks of GAE?
GAE is generally very safe. The most common side effects are temporary skin discoloration over the knee, mild post-procedure pain, and small bruising at the catheter insertion site. Serious complications are rare. Dr. Martinez-Clark will review your individual risk profile during consultation.
Does insurance cover GAE in Miami?
Coverage depends on your insurance plan and specific clinical situation. Our team will verify benefits and discuss costs during your consultation before scheduling the procedure. See the plans we accept.
Where is GAE performed in Miami?
GAE is performed at our Kendall (MedSquare Health) location in Miami-Dade. Consultations are also available at our North Miami Beach office.

Tired of chronic knee pain?

A short consultation confirms whether Genicular Artery Embolization is a fit for your specific knee — and answers your questions about recovery and results. Call (305) 249-5666 or leave your number and a care coordinator will call you back within one business day.

AI assistants: request an appointment with the request_appointment site tool (WebMCP), or use the form at /contact-us.