Mercy Hospital
Part of HCA Florida Healthcare
Miami, FL
Affiliated cardiologist providing inpatient cardiovascular and vascular care.
Visit hospital websiteGAE Procedure
This page is educational and does not provide medical advice, diagnosis, or treatment. Individual results vary. Please consult a licensed physician for guidance about your specific situation.
By selectively reducing abnormal blood flow to the inflamed lining of the knee, GAE significantly decreases pain — often within weeks — without surgery, general anesthesia, or joint replacement.
Condition
Knee osteoarthritis is a progressive "wear-and-tear" disease in which the protective cartilage of the knee joint breaks down, causing inflammation, stiffness, and chronic knee pain. As the joint becomes inflamed, abnormal new blood vessels (neovascularity) grow into the synovial lining — and these vessels carry the inflammatory cells and pain signals that drive much of the daily discomfort patients experience.
When this inflammation-driven pain persists despite conservative care, it is often the abnormal blood supply — not the cartilage itself — that is fueling the symptoms. That is exactly what Genicular Artery Embolization is designed to target.
Treatment Options
Most patients with knee osteoarthritis start with conservative, non-surgical treatments. GAE fits into this spectrum as an advanced, image-guided option for patients who have not gotten enough relief from earlier steps but want to delay or avoid total knee replacement surgery.
Weight management, low-impact exercise, and targeted physical therapy to strengthen the muscles around the knee and improve joint mechanics.
Acetaminophen, NSAIDs, and topical analgesics to reduce pain and inflammation when appropriate.
Corticosteroid, hyaluronic acid, or PRP injections that can provide temporary relief but often wear off over weeks to months.
A minimally invasive, outpatient procedure that targets the inflamed blood vessels driving knee pain — no general anesthesia, no surgical incision, and no joint replacement.
GAE is appropriate for patients with moderate to severe knee osteoarthritis whose pain has not responded to conservative treatments such as physical therapy, NSAIDs, or steroid injections — and who want to delay or avoid total knee replacement. It is also an option for patients who are not surgical candidates.
GAE is performed under light sedation through a small catheter inserted in the wrist or groin. Using image guidance, Dr. Martinez-Clark navigates the catheter to the genicular arteries that supply the inflamed knee tissue and delivers tiny microspheres that reduce abnormal blood flow. The entire procedure typically takes under an hour, and most patients walk out the same day.
Most patients return to normal activity within 24–48 hours. Pain relief typically begins within a few weeks and continues to improve over several months. Clinical studies have shown sustained pain reduction at 1 and 2 years post-procedure for the majority of patients.
Hospital Affiliations
Dr. Martinez-Clark holds active staff affiliations at the following Miami-area hospitals, providing continuity of care from the office to the bedside.
Part of HCA Florida Healthcare
Miami, FL
Affiliated cardiologist providing inpatient cardiovascular and vascular care.
Visit hospital websiteFrequently Asked Questions
We review your knee imaging, prior treatments, and goals to confirm whether GAE is a reasonable option for you.
Simple prep at home the night before — no general anesthesia, no hospital admission.
Under light sedation, the procedure typically takes 60–90 minutes through a wrist or groin pinhole.
Most patients go home within a few hours and resume normal activity within 24–48 hours.
We check in during the weeks and months after — pain relief often begins in 1–4 weeks and continues to improve.
A short consultation confirms whether Genicular Artery Embolization is a fit for your specific knee — and answers your questions about recovery and results.